B23 may refer to:
- A human nucleolar protein also known as NPM1
- The 2.3L, pre-revision variant of the Volvo Redblock engine
- Bundesstraße 23, federal highway in Germany
- B-23, national highway in Catalonia
- B-23 Dragon, a 1930s bomber aircraft
- B-23 (Michigan county highway)
- DLR B23 stock, a passenger train on the Docklands Light Railway in London, UK
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