CYP2D6

CYP2D6
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2F9Q, 3QM4, 3TBG, 3TDA, 4WNT, 4WNU, 4WNV, 4WNW, 4XRY, 4XRZ
Dynodwyr
Cyfenwau	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1, cytochrome P450 family 2 subfamily D member 6, Cytochrome P450 2D6
Dynodwyr allanol	OMIM: 124030 HomoloGene: 133550 GeneCards: CYP2D6
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• iron ion binding; • metal ion binding; • heme binding; • GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; • oxidoreductase activity; • aromatase activity; • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; • steroid hydroxylase activity; • monooxygenase activity;
Cydrannau o'r gell	• organelle membrane; • endoplasmic reticulum membrane; • bilen; • intracellular membrane-bounded organelle; • Reticwlwm endoplasmig; • mitocondria; • cytoplasm;
Prosesau biolegol	• steroid metabolic process; • alkaloid metabolic process; • coumarin metabolic process; • lipid metabolism; • isoquinoline alkaloid metabolic process; • GO:1900774, GO:1900783, GO:1900795, GO:1901084, GO:1900780, GO:1900777, GO:1900771, GO:1901014, GO:1902180, GO:1900987, GO:1900990 alkaloid catabolic process; • oxidative demethylation; • heterocycle metabolic process; • negative regulation of binding; • monoterpenoid metabolic process; • xenobiotic metabolic process; • arachidonic acid metabolic process; • negative regulation of cellular organofluorine metabolic process; • long-chain fatty acid biosynthetic process; • organic acid metabolic process;
	Sources:Amigo / QuickGO
Orthologau
	1565
	n/a
ENSG00000100197; ENSG00000275211; ENSG00000280905; ENSG00000282966; ENSG00000283284;
	ENSG00000272532
	n/a
	P10635
	n/a
	NM_000106; NM_001025161
	n/a
	NP_000097; NP_001020332
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYP2D6 yw CYP2D6 a elwir hefyd yn Cytochrome P450 family 2 subfamily D member 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q13.2.^[2]

[1] "Human PubMed Reference:".

[2] CYP2D6 - Cronfa NCBI

[1]

[2]

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CYP2D6

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