ChEBI

Chemical Entities of Biological Interest (ChEBI)

Content
Description	Chemical database
Data types captured	Small chemical compounds
Contact
Research center	European Molecular Biology Laboratory
Laboratory	European Bioinformatics Institute
Primary citation	de Matos et al[1]
Access
Website	www.ebi.ac.uk/chebi
Download URL	ftp.ebi.ac.uk/pub/databases/chebi
Web service URL	www.ebi.ac.uk/chebi/webServices.do
Sparql endpoint	BIO2RDF
Tools
Web	www.ebi.ac.uk/chebi
Miscellaneous
Data release frequency	monthly
Curation policy	Manually curated

Chemical Entities of Biological Interest, also known as ChEBI,^[1][2] is a chemical database and ontology of molecular entities focused on 'small' chemical compounds, that is part of the Open Biomedical Ontologies (OBO) effort at the European Bioinformatics Institute (EBI). The term "molecular entity" refers to any "constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity".^[3] The molecular entities in question are either products of nature or synthetic products which have potential bioactivity. Molecules directly encoded by the genome, such as nucleic acids, proteins and peptides derived from proteins by proteolytic cleavage, are not as a rule included in ChEBI.

ChEBI uses nomenclature, symbolism and terminology endorsed by the International Union of Pure and Applied Chemistry (IUPAC) and nomenclature committee of the International Union of Biochemistry and Molecular Biology (NC-IUBMB).