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Dihidroorotaza

Dihidroorotaza
Dihidroorotaza dimer, Human
Identifikatori
EC broj 3.5.2.3
CAS broj 9024-93-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Dihidroorotaza (EC 3.5.2.3, karbamoilaspartinska dehidraza, dihidroorotatna hidrolaza) je enzim sa sistematskim imenom (S)-dihidroorotat amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(S)-dihidroorotat + H2O N-karbamoil-L-aspartat
  1. Cooper, C. and Wilson, D.W. (1954). „Biosynthesis of pyrimidines”. Fed. Proc. 13: 194-194. 
  2. Lieberman, I. and Kornberg, A. (1954). „Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. II. Dihydroorotic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin”. J. Biol. Chem. 207: 911-924. PMID 13163076. 

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