Kairo (band), Mexican boy band from 1993 to 1999 with Eduardo Verástegui as member until 1996
Kairo (video game), independently published exploration video game made by Richard Perrin
Kairo (film), A.K.A. Pulse, a 2001 Japanese film directed by Kiyoshi Kurosawa
Kairo-kō, a 1905 novel by Japanese author Natsume Sōseki
Kai-ro, a superhero in episodes of Batman Beyond and Justice League Unlimited cartoons (a future Green Lantern), named after Green Lantern's alien sidekick Kairo.
Kairō, a cloister-like part of a Japanese Buddhist temple