MTPN

MTPN
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3AAA
Identifiers
Aliases	MTPN, GCDP, V-1, myotrophin
External IDs	OMIM: 606484; MGI: 99445; HomoloGene: 40607; GeneCards: MTPN; OMA:MTPN - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	135,977,359 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	35,516,823 bp
RNA expression pattern
	Top expressed in
	cardiac muscle tissue of right atrium; ; skin of arm; ; mucosa of ileum; ; myocardium of left ventricle; ; superficial temporal artery; ; monocyte; ; lower lobe of lung; ; trabecular bone; ; Brodmann area 46; ; tibialis anterior muscle;
	Top expressed in
	retinal pigment epithelium; ; Rostral migratory stream; ; barrel cortex; ; ciliary body; ; epithelium of lens; ; dorsal striatum; ; endothelial cell of lymphatic vessel; ; subiculum; ; prefrontal cortex; ; pineal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding;
Cellular component	cytoplasm; F-actin capping protein complex; axon; perinuclear region of cytoplasm; nucleus; cytosol;
Biological process	regulation of striated muscle tissue development; catecholamine metabolic process; positive regulation of cardiac muscle hypertrophy; regulation of barbed-end actin filament capping; cellular response to mechanical stimulus; skeletal muscle tissue regeneration; neuron differentiation; striated muscle cell differentiation; regulation of translation; cerebellar granule cell differentiation; positive regulation of NF-kappaB transcription factor activity; positive regulation of cell growth; positive regulation of macromolecule biosynthetic process; regulation of cell size;
	Sources:Amigo / QuickGO
Orthologs
	136319
	14489
	ENSG00000105887
	ENSMUSG00000029840
	P58546
	P62774
	NM_145808
	NM_008098
	NP_665807
	NP_032124
	Wikidata
View/Edit Human	View/Edit Mouse

Myotrophin is a protein that in humans is encoded by the MTPN gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105887 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029840 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mitra S, Timur AA, Gupta S, Wang Q, Sen S (July 2001). "Assignment of myotrophin to human chromosome band 7q33→q35 by in situ hybridization". Cytogenet Cell Genet. 93 (1–2): 151–2. doi:10.1159/000056974. PMID 11474205. S2CID 30646120.
^ "Entrez Gene: MTPN myotrophin".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105887 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000029840 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11474205-5] Mitra S, Timur AA, Gupta S, Wang Q, Sen S (July 2001). "Assignment of myotrophin to human chromosome band 7q33→q35 by in situ hybridization". Cytogenet Cell Genet. 93 (1–2): 151–2. doi:10.1159/000056974. PMID 11474205. S2CID 30646120.

[entrez-6] "Entrez Gene: MTPN myotrophin".

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MTPN

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