NR3C1

NR3C1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1M2Z, 1NHZ, 1P93, 3BQD, 3CLD, 3E7C, 3H52, 3K22, 3K23, 4CSJ, 4HN5, 4HN6, 4LSJ, 4MDD, 4P6W, 4P6X, 5CBY, 5CBX, 4UDC, 4UDD, 5CBZ, 5CC1, 5EMQ, 5EMC, 5EMP
Dynodwyr
Cyfenwau	NR3C1, GCCR, GCR, GCRST, GR, GRL, nuclear receptor subfamily 3 group C member 1, Glucocorticoid Receptor
Dynodwyr allanol	OMIM: 138040 HomoloGene: 30960 GeneCards: NR3C1
Patrwm RNA pattern
	; ; ; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• steroid hormone binding; • DNA binding; • sequence-specific DNA binding; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • zinc ion binding; • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific; • glucocorticoid receptor activity; • GO:0038050, GO:0004886, GO:0038051 nuclear receptor activity; • metal ion binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • steroid hormone receptor activity; • steroid binding; • GO:0001948, GO:0016582 protein binding; • lipid binding; • RNA binding; • SUMO binding; • Hsp90 protein binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • protein kinase binding;
Cydrannau o'r gell	• cytoplasm; • nucleoplasm; • mitochondrial matrix; • mitocondria; • cnewyllyn cell; • Cytosgerbwd; • spindle; • microtubule organizing center; • cytosol; • nuclear speck; • GO:0009327 protein-containing complex;
Prosesau biolegol	• cellular response to steroid hormone stimulus; • GO:0009373 regulation of transcription, DNA-templated; • glucocorticoid mediated signaling pathway; • transcription by RNA polymerase II; • transcription initiation from RNA polymerase II promoter; • glucocorticoid receptor signaling pathway; • GO:0072468 signal transduction; • steroid hormone mediated signaling pathway; • cell cycle; • Cellraniad; • GO:0097285 apoptotic process; • chromosome segregation; • GO:1901227 negative regulation of transcription by RNA polymerase II; • transcription, DNA-templated; • cellular response to dexamethasone stimulus; • cellular response to transforming growth factor beta stimulus; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • cellular response to glucocorticoid stimulus; • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization; • positive regulation of pri-miRNA transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologau
	2908
	n/a
	ENSG00000113580
	n/a
	P04150; Q3MSN4
	n/a
NM_000176; NM_001018074; NM_001018075; NM_001018076; NM_001018077;
	NM_001020825; NM_001024094; NM_001204258; NM_001204259; NM_001204260; NM_001204261; NM_001204262; NM_001204263; NM_001204264; NM_001204265; NM_001364180; NM_001364181; NM_001364182; NM_001364183; NM_001364184; NM_001364185
	n/a
NP_000167; NP_001018084; NP_001018085; NP_001018086; NP_001018087;
	NP_001018661; NP_001019265; NP_001191187; NP_001191188; NP_001191189; NP_001191190; NP_001191191; NP_001191192; NP_001191193; NP_001191194; NP_001351109; NP_001351110; NP_001351111; NP_001351112; NP_001351113; NP_001351114; NP_000167.1; NP_001018084.1; NP_001018085.1; NP_001018086.1; NP_001018087.1; NP_001018661.1; NP_001019265.1; NP_001191187.1; NP_001191188.1; NP_001191189.1; NP_001191190.1; NP_001191191.1; NP_001191192.1; NP_001191193.1
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NR3C1 yw NR3C1 a elwir hefyd yn Glucocorticoid receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.3.^[2]

[1] "Human PubMed Reference:".

[2] NR3C1 - Cronfa NCBI

[1]

[2]

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NR3C1

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