NSUN2

NSUN2
Identifiers
Aliases	NSUN2, MISU, MRT5, SAKI, TRM4, NOP2/Sun RNA methyltransferase family member 2, NOP2/Sun RNA methyltransferase 2
External IDs	OMIM: 610916; MGI: 107252; HomoloGene: 9817; GeneCards: NSUN2; OMA:NSUN2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	6,633,291 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	69,783,899 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; right uterine tube; ; secondary oocyte; ; right lobe of liver; ; skin of abdomen; ; appendix; ; skin of leg; ; lymph node; ; pancreatic epithelial cell; ; spleen;
	Top expressed in
	otic placode; ; otic vesicle; ; tail of embryo; ; epiblast; ; saccule; ; Ileal epithelium; ; primitive streak; ; abdominal wall; ; genital tubercle; ; hair follicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	methyltransferase activity; transferase activity; tRNA binding; tRNA (cytosine-5-)-methyltransferase activity; RNA binding;
Cellular component	cytoplasm; chromatoid body; spindle; nucleoplasm; nucleolus; cytoskeleton; nucleus;
Biological process	tRNA methylation; meiotic cell cycle checkpoint signaling; cell division; tRNA modification; methylation; spermatid development; cell cycle; tRNA processing; hair follicle maturation;
	Sources:Amigo / QuickGO
Orthologs
	54888
	28114
	ENSG00000037474
	ENSMUSG00000021595
	Q08J23
	Q1HFZ0
	NM_001193455; NM_017755
	NM_145354
	NP_001180384; NP_060225
	NP_663329
	Wikidata
View/Edit Human	View/Edit Mouse

NOP2/Sun domain family, member 2 is a protein that in humans is encoded by the NSUN2 gene.^[5] Alternatively spliced transcript variants encoding different isoforms have been noted for the gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000037474 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021595 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "NOP2/Sun domain family, member 2". Retrieved 2011-12-04.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000037474 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021595 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "NOP2/Sun domain family, member 2". Retrieved 2011-12-04.

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NSUN2

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