PTH

PTH
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1BWX, 1ET1, 1FVY, 1HPH, 1HPY, 1HTH, 1ZWA, 1ZWB, 1ZWD, 1ZWE, 1ZWF, 1ZWG, 2L1X, 3C4M
Dynodwyr
Cyfenwau	PTH, PTH1, parathyroid hormone, Parathyroid hormone, FIH1
Dynodwyr allanol	OMIM: 168450 HomoloGene: 266 GeneCards: PTH
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding; • hormone activity; • parathyroid hormone receptor binding; • type 1 parathyroid hormone receptor binding; • protein N-terminus binding; • receptor ligand activity; • peptide hormone receptor binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• intracellular anatomical structure; • extracellular region; • extracellular space;
Prosesau biolegol	• positive regulation of signal transduction; • positive regulation of cell proliferation in bone marrow; • positive regulation of osteoclast proliferation; • response to fibroblast growth factor; • hormone-mediated apoptotic signaling pathway; • cAMP metabolic process; • response to ethanol; • response to parathyroid hormone; • skeletal system development; • positive regulation of ossification; • response to lead ion; • response to nutrient levels; • G protein-coupled receptor signaling pathway; • response to vitamin D; • negative regulation of apoptotic process in bone marrow cell; • GO:1901227 negative regulation of transcription by RNA polymerase II; • cellular macromolecule biosynthetic process; • cellular calcium ion homeostasis; • homeostasis of number of cells within a tissue; • response to cadmium ion; • Rho protein signal transduction; • positive regulation of glucose import; • positive regulation of glycogen biosynthetic process; • bone resorption; • positive regulation of bone mineralization; • regulation of gene expression; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • cell-cell signaling; • activation of phospholipase C activity; • negative regulation of chondrocyte differentiation; • positive regulation of inositol phosphate biosynthetic process; • negative regulation of bone mineralization involved in bone maturation; • regulation of signaling receptor activity; • adenylate cyclase-activating G protein-coupled receptor signaling pathway; • calcium ion transport; • magnesium ion homeostasis; • bone mineralization; • phosphate ion homeostasis; • calcium ion homeostasis; • negative regulation of calcium ion transport;
	Sources:Amigo / QuickGO
Orthologau
	5741
	n/a
	ENSG00000152266
	n/a
	P01270
	n/a
	NM_000315; NM_001316352
	n/a
	NP_000306; NP_001303281
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PTH yw PTH a elwir hefyd yn Parathyroid hormone (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11p15.3.^[2]

[1] "Human PubMed Reference:".

[2] PTH - Cronfa NCBI

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