Takalcitol

Takalcitol

(IUPAC) ime
(1S,3R,5Z,7E,24R)-9,10-sekoholesta-5,7,10-trien-1,3,24-triol
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	57333-96-7
ATC kod	D05AX04
PubChem[1][2]	5283734
UNII	C2W72OJ5ZU Y
ChEMBL[3]	CHEMBL340361 Y
Hemijski podaci
Formula	C27H44O3
Mol. masa	416,64
InChI InChI=1S/C27H44O3/c1-17(2)25(29)13-8-18(3)23-11-12-24-20(7-6-14-27(23,24)5)9-10-21-15-22(28)16-26(30)19(21)4/h9-10,17-18,22-26,28-30H,4,6-8,11-16H2,1-3,5H3/b20-9+,21-10-/t18-,22-,23-,24+,25-,26+,27-/m1/s1 Y Key: BJYLYJCXYAMOFT-RSFVBTMBSA-N Y
Sinonimi	(1α,24R)-1,24-Dihidroksivitamin D3
Farmakoinformacioni podaci
Trudnoća	?
Pravni status
Način primene	Topikalno

Takalcitol (1,24-dihidroksivitamin D₃) je sintetički analog vitamina D₃.^[4] Takalcitol je u prodaji pod mnoštvom naziva, uključujući Curatoderm i Bonalfa.

1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
4. ↑ Fukuoka M, Sakurai K, Ohta T, Kiyoki M, Katayama I (2001). „Tacalcitol, an active vitamin D3, induces nerve growth factor production in human epidermal keratinocytes”. Skin Pharmacol. Appl. Skin Physiol. 14 (4): 226–33. DOI:10.1159/000056351. PMID 11464105.