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CXC chemokine receptors
| CXCR1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL8RA | ||||||
| NCBI gene | 3577 | ||||||
| OMIM | 146929 | ||||||
| RefSeq | NM_000634 | ||||||
| UniProt | P25024 | ||||||
| Other data | |||||||
| Locus | Chr. 2 q35 | ||||||
| |||||||
| CXCR2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL8RB | ||||||
| NCBI gene | 3579 | ||||||
| OMIM | 146928 | ||||||
| RefSeq | NM_001557 | ||||||
| UniProt | P25025 | ||||||
| Other data | |||||||
| Locus | Chr. 2 q35 | ||||||
| |||||||
| CXCR3 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CXCR3 | ||||||
| NCBI gene | 2833 | ||||||
| OMIM | 300574 | ||||||
| RefSeq | NM_001504 | ||||||
| UniProt | P49682 | ||||||
| Other data | |||||||
| Locus | Chr. X q13 | ||||||
| |||||||
| CXCR4 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CXCR4 | ||||||
| NCBI gene | 7852 | ||||||
| OMIM | 162643 | ||||||
| RefSeq | NM_001008540 | ||||||
| UniProt | P61073 | ||||||
| Other data | |||||||
| Locus | Chr. 2 q21 | ||||||
| |||||||
| CXCR5 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | BLR1 | ||||||
| NCBI gene | 643 | ||||||
| OMIM | 601613 | ||||||
| RefSeq | NM_001716 | ||||||
| UniProt | P32302 | ||||||
| Other data | |||||||
| Locus | Chr. 11 q23 | ||||||
| |||||||
| CXCR6 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CXCR6 | ||||||
| NCBI gene | 10663 | ||||||
| OMIM | 605163 | ||||||
| RefSeq | NM_006564 | ||||||
| UniProt | O00574 | ||||||
| Other data | |||||||
| Locus | Chr. 3 p21 | ||||||
| |||||||
CXC chemokine receptors are integral membrane proteins that specifically bind and respond to cytokines of the CXC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins, since they span the cell membrane seven times. There are currently six known CXC chemokine receptors in mammals, named CXCR1 through CXCR6.[1][2]
- ^ Bachelerie, Françoise; Graham, Gerard J; Locati, Massimo; Mantovani, Alberto; Murphy, Philip M; Nibbs, Robert; Rot, Antal; Sozzani, Silvano; Thelen, Marcus (2015). "An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15". British Journal of Pharmacology. 172 (16): 3945–3949. doi:10.1111/bph.13182. ISSN 0007-1188. PMC 4543604. PMID 25958743.
- ^ "Gene group: C-X-C motif chemokine receptors (CXCR)". HUGO Gene Nomenclature Committee.
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