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Chronic pancreatitis

Chronic pancreatitis
Other namesPancreatitis – chronic – discharge[1]
Axial CT showing multiple calcifications in the pancreas in a patient with chronic pancreatitis
SpecialtyGastroenterology Edit this on Wikidata
SymptomsNausea and vomiting[1][2]
ComplicationsExocrine pancreatic insufficiency, Endocrine pancreatic insufficiency (Type 3c diabetes), pancreatic pseudocyst,[3] pancreatic cancer,[3] vitamin deficiency (fat-soluble vitamins)[3]
CausesAlcohol(ism), Immune disorder[4]
Diagnostic methodSerum trypsinogen, Fecal fat test[1]
TreatmentPain medicines, avoiding alcohol(and smoking), among other possible management efforts[1]
Frequency50 per 100,000 persons (prevalence)

Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions.[1] It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption. It is a disease process characterized by irreversible damage to the pancreas as distinct from reversible changes in acute pancreatitis.[5][6] Tobacco smoke and alcohol misuse are two of the most frequently implicated causes, and the two risk factors are thought to have a synergistic effect with regards to the development of chronic pancreatitis.[3] Chronic pancreatitis is a risk factor for the development of pancreatic cancer.[3]

  1. ^ a b c d e MedlinePlus Encyclopedia: Chronic pancreatitis
  2. ^ Cite error: The named reference uni_chicago_medicine was invoked but never defined (see the help page).
  3. ^ a b c d e Cite error: The named reference Vege 2022 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference emed was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Brock Nielsen Lelic Drewes Pathophysiology of chronic pancreatitis was invoked but never defined (see the help page).
  6. ^ Oiseth S, Jones L, Maza E, eds. (11 November 2020). "Chronic Pancreatitis". The Lecturio Medical Concept Library. Archived from the original on 9 July 2021. Retrieved 9 July 2021.

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