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Cryptococcus neoformans

Cryptococcus neoformans
Yeast state of Cryptococcus neoformans
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Fungi
Division: Basidiomycota
Class: Tremellomycetes
Order: Tremellales
Family: Cryptococcaceae
Genus: Cryptococcus
Species:
C. neoformans
Binomial name
Cryptococcus neoformans
(San Felice) Vuill. (1901)
Synonyms

Saccharomyces neoformans San Felice (1895)
Filobasidiella neoformans Kwon-Chung (1975)

Cryptococcus neoformans is an encapsulated basidiomycetous yeast[1] belonging to the class Tremellomycetes and an obligate aerobe[2] that can live in both plants and animals. Its teleomorph is a filamentous fungus, formerly referred to Filobasidiella neoformans. In its yeast state, it is often found in bird excrement. It has remarkable genomic plasticity and genetic variability between its strains, making treatment of the disease it causes difficult.[3] Cryptococcus neoformans causes disease primarily in immunocompromised hosts, such as HIV or cancer patients.[1][4][5] In addition it has been shown to cause disease in apparently immunocompetent hosts, especially in developed countries.

  1. ^ a b Buchanan, Kent; Murphy, J. W. (1998). "What makes Cryptococcus neoformans a pathogen?". Emerging Infectious Diseases. 4 (1): 71–83. doi:10.3201/eid0401.980109. PMC 2627665. PMID 9452400.
  2. ^ Ingavale, Susham S.; Chang, Yun C.; Lee, Hyeseung; McClelland, Carol M.; Leong, Madeline L.; Kwon-Chung, Kgung J. (2008-09-01). "Importance of mitochondria in survival of Cryptococcus neoformans under low oxygen conditions and tolerance to Cobalt Chloride". PLOS Pathogens. 4 (9): e1000155. doi:10.1371/journal.ppat.1000155. ISSN 1553-7366. PMC 2528940. PMID 18802457.
  3. ^ Cite error: The named reference :0 was invoked but never defined (see the help page).
  4. ^ Bahn, Yong-Sun; Sun, Sheng; Heitman, Joseph; Lin, Xiaorong (2020-09-01). "Microbe Profile: Cryptococcus neoformans species complex". Microbiology. 166 (9): 797–799. doi:10.1099/mic.0.000973. ISSN 1350-0872. PMC 7717486. PMID 32956032.
  5. ^ Cite error: The named reference :1 was invoked but never defined (see the help page).

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