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Draft:Mangotoxin
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Mangotoxin is a small peptide produced in Pseudomonas syringae. It was found to cause apical necrosis in mango plants. It also causes chlorosis in plants by disrupting ornithine and arginine biosynthesis.[1]
The proteins required for mangotoxin biosynthesis are encoded by the genes in mangotoxin biosynthetic operon (mbo): mboA, mboB, mboC, mboD, mboE, and mboF. All of them are required for the synthesis. The mbo-operon is regulated by gene mgoA in mangotoxin generating operon (mgo)[1]. The MgoA protein increases expression of mbo, but lack of MgoA is not enough to silence the mbo.[2]
The mangotoxin related genes and their homologues are common in Pseudomonas, and they also appear also in other phyla, like Burkholderia. Their purpose is to produce toxin to kill other competing microbes, like fungi or oomycetes.[3]
- ^ a b Carrión, Víctor J.; Arrebola, Eva; Cazorla, Francisco M.; Murillo, Jesús; Vicente, Antonio de (2012-05-17). "The mbo Operon Is Specific and Essential for Biosynthesis of Mangotoxin in Pseudomonas syringae". PLOS ONE. 7 (5): e36709. Bibcode:2012PLoSO...736709C. doi:10.1371/journal.pone.0036709. ISSN 1932-6203. PMC 3355146. PMID 22615797.
- ^ Guo, Qiang; Vitro, Caitlin N.; Crawford, Drake M.; Li, Bo (2024-08-15). "A diazeniumdiolate signal in Pseudomonas syringae upregulates virulence factors and promotes survival in plants". Molecular Plant-Microbe Interactions. 37 (11): 776–783. doi:10.1094/MPMI-06-24-0069-R. ISSN 0894-0282. PMID 39146356.
- ^ Kremmydas, Gerasimos F.; Tampakaki, Anastasia P.; Georgakopoulos, Dimitrios G. (2013-04-15). "Characterization of the Biocontrol Activity of Pseudomonas fluorescens Strain X Reveals Novel Genes Regulated by Glucose". PLOS ONE. 8 (4): e61808. Bibcode:2013PLoSO...861808K. doi:10.1371/journal.pone.0061808. ISSN 1932-6203. PMC 3626644. PMID 23596526.
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