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Draft:Yossi Buganim


Yosef (Yossi) Buganim (born March 5, 1977) is an Israeli scientist, professor, and entrepreneur specializing in stem cell biology, nuclear reprogramming, and regenerative medicine. Buganim is an international HHMI (Howard Hughes Medical Institute) scholar and is renowned for his pioneering research in cellular reprogramming, transdifferentiating, and epigenetics, contributing significantly to the understanding of cell fate acquisition and advancing the fields of developmental biology and regenerative medicine.[1][2][3][4][5]

  1. ^ Radwan, Ahmed; Eccleston, Jason; Sabag, Ofra; Marcus, Howard; Sussman, Jonathan; Ouro, Alberto; Rahamim, Moran; Azagury, Meir; Azria, Batia; Stanger, Ben Z.; Cedar, Howard; Buganim, Yosef (2024-09-24). "Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity". Proceedings of the National Academy of Sciences of the United States of America. 121 (39): e2411352121. Bibcode:2024PNAS..12111352R. doi:10.1073/pnas.2411352121. ISSN 1091-6490. PMC 11441492. PMID 39292740.
  2. ^ Azagury, Meir; Buganim, Yosef (2024-04-22). "Unlocking trophectoderm mysteries: In vivo and in vitro perspectives on human and mouse trophoblast fate induction". Developmental Cell. 59 (8): 941–960. doi:10.1016/j.devcel.2024.03.029. ISSN 1878-1551. PMID 38653193.
  3. ^ Lasry, Rachel; Maoz, Noam; Cheng, Albert W.; Yom Tov, Nataly; Kulenkampff, Elisabeth; Azagury, Meir; Yang, Hui; Ople, Cora; Markoulaki, Styliani; Faddah, Dina A.; Makedonski, Kirill; Orzech, Dana; Sabag, Ofra; Jaenisch, Rudolf; Buganim, Yosef (2023-11-14). "Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects". Stem Cell Reports. 18 (11): 2174–2189. doi:10.1016/j.stemcr.2023.09.009. ISSN 2213-6711. PMC 10679652. PMID 37832543.
  4. ^ Sebban, Shulamit; Buganim, Yosef (January 2016). "Nuclear Reprogramming by Defined Factors: Quantity Versus Quality". Trends in Cell Biology. 26 (1): 65–75. doi:10.1016/j.tcb.2015.08.006. ISSN 1879-3088. PMID 26437595.
  5. ^ Buganim, Yosef; Faddah, Dina A.; Jaenisch, Rudolf (June 2013). "Mechanisms and models of somatic cell reprogramming". Nature Reviews. Genetics. 14 (6): 427–439. doi:10.1038/nrg3473. ISSN 1471-0064. PMC 4060150. PMID 23681063.

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