Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.
Electron-capture dissociation
Electron-capture dissociation (ECD) is a method of fragmenting gas-phase ions for structure elucidation of peptides and proteins in tandem mass spectrometry. It is one of the most widely used techniques for activation and dissociation of mass selected precursor ion in MS/MS. It involves the direct introduction of low-energy electrons to trapped gas-phase ions.[1][2]
- ^ Zubarev, Roman A.; Kelleher, Neil L.; McLafferty, Fred W. (1998-04-01). "Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process". Journal of the American Chemical Society. 120 (13): 3265–3266. doi:10.1021/ja973478k. ISSN 0002-7863.
- ^ McLafferty, Fred W.; Horn, David M.; Breuker, Kathrin; Ge, Ying; Lewis, Mark A.; Cerda, Blas; Zubarev, Roman A.; Carpenter, Barry K. (2001-03-01). "Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance". Journal of the American Society for Mass Spectrometry. 12 (3): 245–249. Bibcode:2001JASMS..12..245M. doi:10.1016/s1044-0305(00)00223-3. ISSN 1044-0305. PMID 11281599. S2CID 45275450.
Previous Page Next Page
