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Eva Klein

Eva Klein
photo of Eva and George Klein
Klein with her husband George in 1979
Born
Eva Fischer

(1925-01-22)22 January 1925
Died19 January 2025(2025-01-19) (aged 99)
Alma mater
Known for
Spouse
(m. 1947; died 2016)
Children3
Awards
Scientific career
Fields
  • Tumor biology
  • Cancer immunology
Institutions

Eva Klein (née Eva Fischer; 22 January 1925 – 19 January 2025) was a Hungarian-Swedish scientist. Klein worked at the Karolinska Institute since leaving Hungary in 1947.[1][2] She is regarded as a founder of cancer immunology.

Her life and career choices as a young Jewish woman were constrained by discrimination, and she survived the late stages of German occupation in hiding.[1] A medical doctor with a PhD in biology, she worked in cancer immunology and virology.

In the 1960s, she led the discovery of natural killer cells[3][1] and developing Burkitt's lymphoma cell lines.[4][5] She pursued her own lines of work as well as working closely with her husband, George Klein.[6]

In 1975, the U.S. Cancer Research Institute established the William B. Coley Award for Distinguished Research in Basic and Tumor Immunology. The inaugural award was shared by 16 scientists considered to be "founders of cancer immunology", including Eva and George Klein.[7] Their award noted their "discoveries of tumor-specific antigens in the mouse, to the most comprehensive immunological analysis of a human cancer, Burkitt's lymphoma".[8]

  1. ^ a b c Cite error: The named reference Hargittai was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference MTC-90th-Birthday was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference Kiessling-1975 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Cell-lines-1969-PubMed was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference Bio-CancerImmRes-2015 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference Klein-self was invoked but never defined (see the help page).
  7. ^ "William B. Coley Award". Cancer Research. Cancer Research Institute. Retrieved 5 December 2015.
  8. ^ "Cover Legend" (PDF). Cancer Research. 36 (5). May 1976. Retrieved 5 December 2015.

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إيفا كلاين Arabic ايفا كلاين ARZ Ева Кляйн BA Eva Klein German Εύα Κλάιν Greek Éva Klein EO Eva Klein Spanish Eva Klein French אווה קליין HE Klein Éva Hungarian

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