Eva Nogales | |
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Born | May 16, 1965 Colmenar Viejo, Madrid, Spain | (age 59)
Alma mater | B.S., physics, Autonomous University of Madrid in 1988, PhD, University of Keele, 1992 |
Occupation(s) | Biophysicist, professor |
Known for | The first to determine the atomic structure of tubulin by electron crystallography |
Spouse | Howard Padmore |
Children | 2 |
Awards | Early Career Award, American Society for Cell Biology (2005) Chabot Science Award for Excellence (2006) Shaw Prize (2023) |
Scientific career | |
Institutions | University of California, Berkeley, Howard Hughes Medical Institute, Synchrotron Radiation Source |
Eva Nogales (born in Colmenar Viejo, Madrid, Spain) is a Spanish-American biophysicist at the Lawrence Berkeley National Laboratory and a professor at the University of California, Berkeley, where she served as head of the Division of Biochemistry, Biophysics and Structural Biology of the Department of Molecular and Cell Biology (2015–2020). She is a Howard Hughes Medical Institute investigator.
Nogales is a pioneer in using electron microscopy for the structural and functional characterization of macromolecular complexes. She used electron crystallography to obtain the first structure of tubulin and identify the binding site of the important anti-cancer drug taxol. She is a leader in combining cryo-EM, computational image analysis and biochemical assays to gain insights into function and regulation of biological complexes and molecular machines.[1] Her work has uncovered aspects of cellular function that are relevant to the treatment of cancer and other diseases.[2]