Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.
Haemophilus influenzae
| Haemophilus influenzae | |
|---|---|
| |
| H. influenzae on a chocolate agar plate | |
Scientific classification 
| |
| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Gammaproteobacteria |
| Order: | Pasteurellales |
| Family: | Pasteurellaceae |
| Genus: | Haemophilus |
| Species: | H. influenzae
|
| Binomial name | |
| Haemophilus influenzae (Lehmann & Neumann 1896)
Winslow et al. 1917 | |
Haemophilus influenzae (formerly called Pfeiffer's bacillus or Bacillus influenzae) is a Gram-negative, non-motile, coccobacillary, facultatively anaerobic, capnophilic pathogenic bacterium of the family Pasteurellaceae. The bacteria are mesophilic and grow best at temperatures between 35 and 37 °C.[1]
H. influenzae was first described in 1893[2][3] by Richard Pfeiffer during an influenza pandemic[4] when he incorrectly identified it as the causative microbe, which is why the bacteria was given the name "influenzae".[5][6] H. influenzae is responsible for a wide range of localized and invasive infections, typically in infants and children,[7] including pneumonia, meningitis, or bloodstream infections.[8] Treatment consists of antibiotics; however, H. influenzae is often resistant to the penicillin family, but amoxicillin/clavulanic acid can be used in mild cases.[9] Serotype B H. influenzae have been a major cause of meningitis in infants and small children, frequently causing deafness and mental retardation. However, the development in the 1980s of a vaccine effective in this age group (the Hib vaccine) has almost eliminated this in developed countries.
This species was the first organism to have its entire genome sequenced.[10][11]
- ^ "Meningitis, Hib and Pneumococcal Conjugate Vaccines". AAP Grand Rounds. 3 (1): 3–4. 2000-01-01. doi:10.1542/gr.3-1-3-a. ISSN 1099-6605.
- ^ Pfeiffer, R (1893). "Die Aetiologie der Influenza". Zeitschrift für Hygiene und Infektionskrankheiten. 13: 357–385. doi:10.1007/BF02284284. S2CID 38511538.
- ^ "Deep Blue: Search". deepblue.lib.umich.edu.
- ^ Kuhnert P, Christensen H, eds. (2008). Pasteurellaceae: Biology, Genomics and Molecular Aspects. Caister Academic Press. ISBN 978-1-904455-34-9.
- ^ Morens DM, Taubenberger JK, Folkers GK, Fauci AS (December 2010). "Pandemic influenza's 500th anniversary". Clinical Infectious Diseases. 51 (12): 1442–1444. doi:10.1086/657429. PMC 3106245. PMID 21067353.
- ^ Taubenberger JK, Hultin JV, Morens DM (2007). "Discovery and characterization of the 1918 pandemic influenza virus in historical context". Antiviral Therapy. 12 (4 Pt B): 581–591. doi:10.1177/135965350701200S02.1. PMC 2391305. PMID 17944266.
- ^ "Pinkbook: Haemophilus influenzae (Hib) | CDC". www.cdc.gov. 2022-09-22. Retrieved 2022-10-13.
- ^ "Symptoms of Haemophilus influenzae | CDC". www.cdc.gov. 2022-04-04. Retrieved 2022-10-20.
- ^ Chang AB, Upham JW, Masters IB, Redding GR, Gibson PG, Marchant JM, Grimwood K (March 2016). "Protracted bacterial bronchitis: The last decade and the road ahead". Pediatric Pulmonology. 51 (3): 225–242. doi:10.1002/ppul.23351. PMC 7167774. PMID 26636654.
- ^ Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, et al. (July 1995). "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd". Science. 269 (5223): 496–512. Bibcode:1995Sci...269..496F. doi:10.1126/science.7542800. PMID 7542800. S2CID 10423613.
- ^ "About J. Craig Venter Institute". J. Craig Venter Institute.
Previous Page Next Page
