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Mascot (software)

Mascot
Original author(s)David Perkins and Darryl Pappin
Initial release1999 (1999)
Stable release
2.6.00 / December 2016 (2016-12)
Operating systemLinux or Windows
Available inC
TypeProtein identification Bioinformatics
Licenseproprietary, free for online use
Websitehttp://www.matrixscience.com/

Mascot is a software search engine that uses mass spectrometry data to identify proteins from peptide sequence databases.[1][2] Mascot is widely used by research facilities around the world. Mascot uses a probabilistic scoring algorithm for protein identification that was adapted from the MOWSE algorithm. Mascot is freely available to use on the website of Matrix Science.[3] A license is required for in-house use where more features can be incorporated.

  1. ^ Perkins DN, Pappin DJ, Creasy DM, Cottrell JS (December 1999). "Probability-based protein identification by searching sequence databases using mass spectrometry data". Electrophoresis. 20 (18): 3551–67. doi:10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2. PMID 10612281.
  2. ^ Koenig T, Menze BH, Kirchner M, et al. (September 2008). "Robust prediction of the MASCOT score for an improved quality assessment in mass spectrometric proteomics". J. Proteome Res. 7 (9): 3708–17. doi:10.1021/pr700859x. PMID 18707158.
  3. ^ Mascot software, Matrix Science.

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