Missouri Route 72

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Route 72
Route information
Maintained by MoDOT
Length	165.675 mi (266.628 km)
Existed	1922–present
Major junctions
West end	I-44 BL in Rolla
Major intersections	US 63 in Rolla US 67 in Fredericktown
East end	I-55 BL / US 61 / Route 25 in Jackson
Location
Country	United States
State	Missouri
Highway system
Missouri State Highway System Interstate US State Supplemental
← I-72 → Route 73

Route 72 is a highway in southern Missouri. Its eastern terminus is at Route 34 west of Jackson; its western terminus is at I-44 in Rolla.

Route 72 is one of the original 1922 state highways. Its eastern terminus was at Centerville, and its western terminus was at the junction with Route 32. The part between Arcadia and Fredericktown was Route 70 from 1922 to 1959, when it became part of Route 72 because of I-70. Route 72 was rebuilt a few years back from Elk Prairie, just south of Rolla; to the intersection of Hwy 32, west of Salem. The road was widened and shoulders were built.