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NBoc-DMT
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| Clinical data | |
|---|---|
| Other names | NB-DMT; DMT-BOC; N′-t-BOC-DMT; N′-tert-Butoxycarbonyl-N,N-dimethyltryptamine |
| Drug class | Serotonergic psychedelic; Hallucinogen; Serotonin receptor agonist; Serotonin 5-HT2A receptor agonist |
| Legal status | |
| Legal status |
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| Identifiers | |
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| PubChem CID | |
| Chemical and physical data | |
| Formula | C17H24N2O2 |
| Molar mass | 288.391 g·mol−1 |
| 3D model (JSmol) | |
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NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family.[1][2] It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′-tert-butyloxycarbonyl (NBoc) group.[1][2]
NB-DMT is said to be a "prodrug" of DMT that decomposes into DMT when the compound is heated (e.g., with smoking or vaping).[1] It may also be useful as an orally active prodrug of DMT, unlike DMT itself which is inactive when taken orally.[3][4] NB-DMT has been claimed to have about 25% of the potency of DMT by weight.[1]
It was first detected as a designer drug being sold online by February 2024.[1] NB-DMT is a Schedule I controlled substance in Russia.[1] A number of other NBoc designer drugs have also been encountered.[1][5]
- ^ a b c d e f g "DMT BOC (NB-DMT)". АИПСИН (AIPSIN) (in Russian). Retrieved 23 January 2025.
- ^ a b "Tert-butyl 3-[2-(dimethylamino)ethyl]indole-1-carboxylate". PubChem. U.S. National Library of Medicine. Retrieved 23 January 2025.
- ^ US 2024/0116870, Alexander M, Duncton J, Clark S, "N,N-dimethyltryptamine and related psychedelics and uses thereof.", published 11 April 2024, assigned to Terran Biosciences Inc.
- ^ WO 2024/121253, Buchner M, "Novel N,N-Dimethyltryptamine (DMT) derivatives and uses thereof.", published 13 June 2024, assigned to Mihkal GmbH
- ^ Johnson CS, Bogun B (2019). "Chemical camouflage: illicit drug concealment using di-tert-butyldicarbonate". Australian Journal of Forensic Sciences. 51: S217 – S219. doi:10.1080/00450618.2019.1569135. S2CID 86747489.
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