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One Health is an approach calling for "the collaborative efforts of multiple disciplines working locally, nationally, and globally, to attain optimal health for people, animals and our environment", as defined by the One Health Initiative Task Force (OHITF).[2] It developed in response to evidence of the spreading of zoonotic diseases between species and increasing awareness of "the interdependence of human and animal health and ecological change".[3]: 205 [4] In this viewpoint, public health is no longer seen in purely human terms.[5][6] Due to a shared environment and highly conserved physiology, animals and humans not only suffer from the same zoonotic diseases but can also be treated by either structurally related or identical drugs. For this reason, special care must be taken to avoid unnecessary or over-treatment of zoonotic diseases, particularly in the context of drug resistance in infectious microbes.[7]
A number of organizations throughout the world support the objectives of "One Health" including the One Health Commission (OHC), One Health Initiative, One Health Platform, CDC One Health Office, and the Quadripartite Organizations. The Quadripartite Organizations are:
In particular, the One Health High Level Expert Panel, an independent advisory group to the Quadripartite Organizations,[8] provided a comprehensive definition of One Health, whereby:
"One Health is an integrated, unifying approach that aims to sustainably balance and optimize the health of humans, animals, plants and ecosystems. It recognizes the health of humans, domestic and wild animals, plants and the wider environment (including ecosystems) are closely linked and interdependent. The approach mobilizes multiple sectors, disciplines and communities at varying levels of society to work together to foster well-being and tackle threats to health and ecosystems, while addressing the collective need for clean water, energy and air, safe and nutritious food, taking action on climate change, and contributing to sustainable development."[8]
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