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President's Emergency Plan for AIDS Relief

The PEPFAR logo

The United States President's Emergency Plan For AIDS Relief (PEPFAR) is the global health funding by the United States to address the global HIV/AIDS epidemic and help save the lives of those suffering from the disease. The U.S. allocation of over $110 billion marks the largest investment by any country has ever made towards combating a single disease.[1] As of 2023, PEPFAR has saved over 25 million lives,[2][3] primarily in sub-Saharan Africa.[4][5]

Launched by U.S. President George W. Bush in 2003, as of May 2020, PEPFAR has provided cumulative funding for HIV/AIDS treatment, prevention, and research since its inception, making it the largest global health program focused on a single disease in history until the COVID-19 pandemic.[4] PEPFAR is implemented by a combination of U.S. government agencies in over 50 countries and overseen by the Global AIDS Coordinator at the United States Department of State.[6]

The PEPFAR program has in recent years been criticized by members of the Republican Party who have sought to block its re-authorization.[7] In 2025, the Donald Trump administration put the program on halt and took PEPFAR’s computer systems offline.[7]

  1. ^ "PEPFAR: Two Decades of Global Progress Against HIV | Aspen Ideas". Aspen Ideas Festival. Retrieved October 27, 2024.
  2. ^ "PEPFAR - HIV.gov". March 2, 2023. Retrieved July 2, 2023.
  3. ^ Beauchamp, Zack (July 28, 2023). "Republicans are threatening to sabotage George W. Bush's greatest accomplishment". Vox. Retrieved July 29, 2023.
  4. ^ a b "The U.S. President's Emergency Plan for AIDS Relief (PEPFAR)". The Henry J. Kaiser Family Foundation. May 27, 2020. Retrieved March 30, 2021.
  5. ^ Fauci, Anthony S.; Eisinger, Robert W. (January 25, 2018). "PEPFAR — 15 Years and Counting the Lives Saved". New England Journal of Medicine. 378 (4): 314–316. doi:10.1056/NEJMp1714773. ISSN 0028-4793. PMID 29365298.
  6. ^ "About Us". www.pepfar.gov. Retrieved March 26, 2019.
  7. ^ a b Mandavilli, Apoorva (January 27, 2025). "Trump Administration Halts H.I.V. Drug Distribution in Poor Countries". The New York Times. ISSN 0362-4331. Retrieved January 28, 2025.

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