Protein Data Bank

Protein Data Bank

Content
Description	Protein structure X-ray crystallography NMR Structure Determination
Contact
Primary citation	PMID 30357364
Access
Data format	mmCIF, PDB
Website	www.wwpdb.org ebi.ac.uk www.rcsb.org bmrb.io pdbj.org

The Protein Data Bank (PDB)^[1] is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, which is overseen by the Worldwide Protein Data Bank (wwPDB). These structural data are obtained and deposited by biologists and biochemists worldwide through the use of experimental methodologies such as X-ray crystallography, NMR spectroscopy, and, increasingly, cryo-electron microscopy. All submitted data are reviewed by expert biocurators and, once approved, are made freely available on the Internet under the CC0 Public Domain Dedication.^[2] Global access to the data is provided by the websites of the wwPDB member organisations (PDBe,^[3] PDBj,^[4] RCSB PDB,^[5] and BMRB^[6]).

The PDB is a key in areas of structural biology, such as structural genomics. Most major scientific journals and some funding agencies now require scientists to submit their structure data to the PDB. Many other databases use protein structures deposited in the PDB. For example, SCOP and CATH classify protein structures, while PDBsum provides a graphic overview of PDB entries using information from other sources, such as Gene Ontology.^[7][8]