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Sinusitis

Sinusitis
Other namesSinus infection, rhinosinusitis
An illustration showing the difference between healthy sinuses and diseased sinuses
SpecialtyOtorhinolaryngology
Symptomsnasal discharge, nasal blockage, facial pain, reduction or loss of smell, fever[1][2]
CausesInfection (bacterial, fungal, viral), allergies, air pollution, structural problems in the nose[3]
Risk factorsAsthma, cystic fibrosis, poor immune function[1]
Diagnostic methodUsually based on symptoms
Differential diagnosiscommon cold, rhinitis, upper respiratory infection, temporomandibular joint disorder, tension headache, vascular headache, dental infection
Preventionhandwashing, vaccinations, avoiding smoking[3]
TreatmentPain medications, nasal steroids, nasal irrigation, antibiotic[1][4]
Frequency10–30% each year (developed world)[1][5]

Sinusitis, also known as rhinosinusitis, is an inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include production of thick nasal mucus, nasal congestion, facial congestion, facial pain, facial pressure, loss of smell, or fever.[6][7]

Sinusitis is a condition that affects both children and adults. It is caused by a combination of environmental and a person's individual health factors.[8] It can occur in individuals with allergies, exposure to environmental irritants, structural abnormalities of the nasal cavity and sinuses and poor immune function.[9] Most cases are caused by a viral infection.[3] Recurrent episodes are more likely in persons with asthma, cystic fibrosis, and immunodeficiency.[10]

The diagnosis of sinusitis is based on the symptoms and their duration along with signs of disease identified by endoscopic and/or radiologic criteria.[11] Sinusitis is classified into acute sinusitis and chronic sinusitis. In acute sinusitis, symptoms last for less than 4 weeks. In chronic sinusitis symptoms must be present for at least 12 weeks.[12] In the initial evaluation of sinusitis an Otolaryngologist, also known as an ear, nose and throat (ENT) doctor, may confirm sinusitis using nasal endoscopy.[11] Diagnostic imaging is not usually needed in acute stage unless complications are suspected.[13] In chronic cases, confirmatory testing is recommended by use of computed tomography.[13]

Prevention of sinusitis focuses on regular hand washing, staying up-to date on vaccinations, and avoiding smoking.[14] Pain killers such as naproxen, nasal steroids, and nasal irrigation may be used to help with symptoms.[15][16] Recommended initial treatment for acute sinusitis is watchful waiting.[15] If symptoms do not improve in 7–10 days or worsen, then an antibiotic may be implemented or changed.[15] In those in whom antibiotics are indicated, either amoxicillin or amoxicillin/clavulanate is recommended first line, with amoxicillin/clavulanate being superior to amoxicillin alone but with more side effects.[17][15] Surgery may be recommended in those with chronic disease who have failed medical management.[18]

Sinusitis is a common condition.[19] It affects between about 10 and 30 percent of people each year in the United States and Europe.[19][5] The management of sinusitis in the United States results in more than US$11 billion in costs.[19]

  1. ^ a b c d Cite error: The named reference pmid25833927 was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference pmid27113482 was invoked but never defined (see the help page).
  3. ^ a b c "Sinus Infection (Sinusitis)". cdc.gov. September 30, 2013. Archived from the original on 7 April 2015. Retrieved 6 April 2015.
  4. ^ Cite error: The named reference pmid25892369 was invoked but never defined (see the help page).
  5. ^ a b Adkinson NF (2014). Middleton's allergy: principles and practice (Eight ed.). Philadelphia: Elsevier Saunders. p. 687. ISBN 9780323085939. Archived from the original on 2016-06-03.
  6. ^ Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Kumar KA, Kramper M, et al. (April 2015). "Clinical practice guideline (update): Adult Sinusitis Executive Summary". Otolaryngology–Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927. S2CID 206469424.
  7. ^ Head K, Chong LY, Piromchai P, Hopkins C, Philpott C, Schilder AG, et al. (April 2016). "Systemic and topical antibiotics for chronic rhinosinusitis" (PDF). The Cochrane Database of Systematic Reviews. 2016 (4): CD011994. doi:10.1002/14651858.CD011994.pub2. PMC 8763400. PMID 27113482. S2CID 205210696. Archived (PDF) from the original on 2018-07-22. Retrieved 2019-09-17.
  8. ^ Battisti AS, Modi P, Pangia J (2024), "Sinusitis", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 29262090, archived from the original on 2023-11-18, retrieved 2024-11-12
  9. ^ Adkinson NF (2014). Middleton's allergy: principles and practice (Eight ed.). Philadelphia: Elsevier Saunders. p. 687. ISBN 9780323085939. Archived from the original on 2016-06-03.
  10. ^ Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Kumar KA, Kramper M, et al. (April 2015). "Clinical practice guideline (update): Adult Sinusitis Executive Summary". Otolaryngology–Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927. S2CID 206469424.
  11. ^ a b Adkinson NF (2014). Middleton's allergy: principles and practice (Eight ed.). Philadelphia: Elsevier Saunders. p. 687. ISBN 9780323085939. Archived from the original on 2016-06-03.
  12. ^ Adkinson NF, Middleton E, eds. (2014). Middleton's allergy: principles and practice (8th ed.). Philadelphia, PA: Elsevier/Saunders. ISBN 978-0-323-08593-9.
  13. ^ a b Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Kumar KA, Kramper M, et al. (April 2015). "Clinical practice guideline (update): Adult Sinusitis Executive Summary". Otolaryngology–Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927. S2CID 206469424.
  14. ^ "Sinus Infection (Sinusitis)". cdc.gov. September 30, 2013. Archived from the original on 7 April 2015. Retrieved 6 April 2015.
  15. ^ a b c d Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Kumar KA, Kramper M, et al. (April 2015). "Clinical practice guideline (update): Adult Sinusitis Executive Summary". Otolaryngology–Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927. S2CID 206469424.
  16. ^ King D, Mitchell B, Williams CP, Spurling GK (April 2015). "Saline nasal irrigation for acute upper respiratory tract infections" (PDF). The Cochrane Database of Systematic Reviews. 2015 (4): CD006821. doi:10.1002/14651858.CD006821.pub3. PMC 9475221. PMID 25892369. Archived (PDF) from the original on 2021-08-29. Retrieved 2018-04-20.
  17. ^ Orlandi RR, Kingdom TT, Smith TL, Bleier B, DeConde A, Luong AU, et al. (2021). "International consensus statement on allergy and rhinology: rhinosinusitis 2021" (PDF). International Forum of Allergy & Rhinology. 11 (3). Wiley: 213–739. doi:10.1002/alr.22741. ISSN 2042-6976. PMID 33236525. S2CID 227165628. Archived (PDF) from the original on 2023-03-07. Retrieved 2023-01-21.
  18. ^ "How Is Sinusitis Treated". April 3, 2012. Archived from the original on 5 April 2015. Retrieved 6 April 2015.
  19. ^ a b c Rosenfeld RM, Piccirillo JF, Chandrasekhar SS, Brook I, Kumar KA, Kramper M, et al. (April 2015). "Clinical practice guideline (update): Adult Sinusitis Executive Summary". Otolaryngology–Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927. S2CID 206469424.

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