Sulston score

The Sulston score is an equation used in DNA mapping to numerically assess the likelihood that a given "fingerprint" similarity between two DNA clones is merely a result of chance. Used as such, it is a test of statistical significance. That is, low values imply that similarity is significant, suggesting that two DNA clones overlap one another and that the given similarity is not just a chance event. The name is an eponym that refers to John Sulston by virtue of his being the lead author of the paper that first proposed the equation's use.^[1]

^ Sulston J, Mallett F, Staden R, Durbin R, Horsnell T, Coulson A (Mar 1988). "Software for genome mapping by fingerprinting techniques". Comput Appl Biosci. 4 (1): 125–32. doi:10.1093/bioinformatics/4.1.125. PMID 2838135.

[sulston1988-1] Sulston J, Mallett F, Staden R, Durbin R, Horsnell T, Coulson A (Mar 1988). "Software for genome mapping by fingerprinting techniques". Comput Appl Biosci. 4 (1): 125–32. doi:10.1093/bioinformatics/4.1.125. PMID 2838135.

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Sulston score

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