Tooth regeneration

Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.^[1]

As a source of the new bioengineered teeth, somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer^[2] in the shape of the new tooth.^[3]

^ Otsu, Keishi; Kumakami-Sakano, Mika; Fujiwara, Naoki; Kikuchi, Kazuko; Keller, Laetitia; Lesot, Hervé; Harada, Hidemitsu (2014). "Stem cell sources for tooth regeneration: current status and future prospects". Frontiers in Physiology. 5: 36. doi:10.3389/fphys.2014.00036. PMC 3912331. PMID 24550845.
^ Kellomäki, Minna; Törmälä, Pertti (2003). "Processing of Resorbable Poly-α-Hydroxy Acids for Use as Tissue-Engineering Scaffolds". Biopolymer Methods in Tissue Engineering. Vol. 238. pp. 1–10. doi:10.1385/1-59259-428-X:1. ISBN 978-1-59259-428-3.
^ Hill, David J. (10 May 2012). "Toothless No More - Researchers Using Stem Cells to Grow New Teeth". Singularity Hub.