U.S. Route 222

U.S. Route 222
US 222 highlighted in red
Route information
Auxiliary route of US 22
Maintained by MDSHA and PennDOT
Length	94.96 mi[1][2] (152.82 km)
Existed	1926–present
Major junctions
South end	US 1 in Conowingo, MD
Major intersections	PA 372 in Quarryville, PA PA 272 in Willow Street, PA US 30 in Lancaster, PA US 322 in Ephrata, PA US 422 near Reading, PA PA 12 near Reading, PA PA 61 near Reading, PA PA 73 in Maiden Creek, PA PA 100 in Trexlertown, PA
North end	I-78 / PA 222 / PA 309 in Dorneyville, PA
Location
Country	United States
States	Maryland, Pennsylvania
Counties	MD: Cecil PA: Lancaster, Berks, Lehigh
Highway system
United States Numbered Highway System List Special Divided
Maryland highway system Interstate US State Scenic Byways
Pennsylvania State Route System Interstate US State Scenic Legislative
← MD 221 MD → MD 222 ← PA 221 PA → PA 222

U.S. Route 222 (US 222) is a U.S. Highway that is a spur of US 22 in the states of Maryland and Pennsylvania. It runs for 95 miles (153 km) from US 1 in Conowingo, Maryland, north to the junction of Interstate 78 (I-78) and Pennsylvania Route 309 (PA 309) in Dorneyville, Pennsylvania. US 222 is almost entirely in Pennsylvania, and serves as the state's principal artery between the Lancaster and Reading areas in the west and the Lehigh Valley in the east.

US 222 heads north from US 1 in Conowingo and soon crosses from Maryland into Pennsylvania, continuing north through rural areas and passing through Quarryville and Willow Street before reaching Lancaster. The route passes through Lancaster on a one-way pair of city streets before becoming a freeway at US 30 north of the city. The US 222 freeway heads northeast, crossing US 322 in Ephrata and coming to an indirect interchange with the Pennsylvania Turnpike (I-76).

US 222 bypasses Reading to the west, where it forms a concurrency with US 422. The freeway section ends past Reading and the route continues northeast through rural areas, with a freeway bypass of Kutztown. US 222 bypasses Trexlertown on a multilane divided expressway before coming to its northern terminus at I-78/PA 309 in Dorneyville, where the road continues into Allentown as PA 222.