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4-Oksalokrotonatna dekarboksilaza
| 4-Oksalokrotonatna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.77 | ||||||||
| CAS broj | 37325-55-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
4-Oksalokrotonatna dekarboksilaza (EC 4.1.1.77, 4-oksalokrotonatna karboksilijaza, cnbF (gen), praD (gen), amnE (gen), nbaG (gen), xylI (gen)) je enzim sa sistematskim imenom (3E)-2-oksoheks-3-endioat karboksilijaza (formira 2-oksopent-4-enoat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (3E)-2-oksoheks-3-enedioat 2-oksopent-4-enoat + CO2
Ovaj enzim učestvuje u degradaciji fenola, modifikovanih fenola i katehola.
- ↑ Shingler, V., Marklund, U., Powlowski, J. (1992). „Nucleotide sequence and functional analysis of the complete phenol/3,4-dimethylphenol catabolic pathway of Pseudomonas sp. strain CF600”. J. Bacteriol. 174: 711-724. PMID 1732207.
- ↑ Takenaka, S., Murakami, S., Shinke, R. and Aoki, K. (1998). „Metabolism of 2-aminophenol by Pseudomonas sp. AP-3: modified meta-cleavage pathway”. Arch. Microbiol. 170: 132-137. PMID 9683650.
- ↑ Stanley, T.M., Johnson, W.H., Jr., Burks, E.A., Whitman, C.P., Hwang, C.C. and Cook, P.F. (2000). „Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase”. Biochemistry 39: 718-726. PMID 10651637.
- ↑ Wang, S.C., Johnson, W.H., Jr., Czerwinski, R.M., Stamps, S.L. and Whitman, C.P. (2007). „Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions”. Biochemistry 46: 11919-11929. PMID 17902707.
- ↑ Kasai, D., Fujinami, T., Abe, T., Mase, K., Katayama, Y., Fukuda, M. and Masai, E. (2009). „Uncovering the protocatechuate 2,3-cleavage pathway genes”. J. Bacteriol. 191: 6758-6768. PMID 19717587.
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