Norfenefrin

Norfenefrin

(IUPAC) ime
3-(2-amino-1-hidroksietil)fenol
Klinički podaci
AHFS/Drugs.com	Internacionalno ime leka
Identifikatori
CAS broj	536-21-0 15308-34-6 (hidrohlorid)
ATC kod	C01CA05
PubChem[1][2]	4538
ChemSpider[3]	4379
UNII	D2P3M6SRN5 Y
KEGG[4]	D08286 Y
ChEMBL[5]	CHEMBL358040 Y
Hemijski podaci
Formula	C8H11NO2
Mol. masa	153,178 g/mol
SMILES	eMolekuli & PubHem
InChI InChI=1S/C8H11NO2/c9-5-8(11)6-2-1-3-7(10)4-6/h1-4,8,10-11H,5,9H2 Y Key: LRCXRAABFLIVAI-UHFFFAOYSA-N Y
Sinonimi	Norfenephrine Norphenephrine Norphenylephrine meta-Norsynephrine meta-Octopamine 3-Octopamine
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	℞ Prescription only

Norfenefrin (Coritat, Energona, Hypolind, Novadral, m-oktopamin, 3-oktopamin, 3,β-dihidroksifenetilamin) je adrenergički lek koji se koristi kao simpatomimetik. On je u prodaji u Evropi, Japanu, i Meksiku.^[6][7] Zajedno sa strukturnim izomerima p-oktopaminom i tiraminom, norfenefrin je prirodni, endogeni trag amin. On deluje kao jedan od pomoćnih neurotransmitera u mozgu.^[8]

1. ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
2. ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
3. ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
4. ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
5. ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.  edit
6. ↑ F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. str. 104. ISBN 978-0-412-46630-4. 
7. ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. str. 750. ISBN 978-3-88763-075-1. Pristupljeno 24. 4. 2012. 
8. ↑ Danielson TJ, Boulton AA, Robertson HA (December 1977). „m-Octopamine, p-octopamine and phenylethanolamine in rat brain: a sensitive, specific assay and the effects of some drugs”. Journal of Neurochemistry 29 (6): 1131–5. PMID 340613.