Butokonazol

Butokonazol
IUPAC ime
	1-[4-(4-hlorofenil)-2-(2,6-dihlorofenil)sulfanilbutil]imidazol
Klinički podaci
Prodajno ime	Femstat, Femstat 3, Gynazole-1, Mycelex-3
Drugs.com	Monografija
Način primene	Intravaginalno
Identifikatori
CAS broj	64872-77-1
ATC kod	G01AF15 (WHO)
PubChem	CID 47472
DrugBank	DB00639
ChemSpider	43192
KEGG	C08066
ChEMBL	CHEMBL1295
Hemijski podaci
Formula	C19H17Cl3N2S
Molarna masa	411,776
	SMILES ClC1=CC=C(CCC(CN2C=CN=C2)SC2=C(Cl)C=CC=C2Cl)C=C1; ;
	InChI InChI=1S/C19H17Cl3N2S/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22/h1-5,7-8,10-11,13,16H,6,9,12H2 ; Key:SWLMUYACZKCSHZ-UHFFFAOYSA-N ;
Fizički podaci
Tačka topljenja	159 °C (318 °F)

Butokonazol (prodajni nazivi Gynazole-1, Mycelex-3) je imidazolni antifungalni lek koji se koristi u ginekologij. On se administerira kao vaginalna krema.^[1]^[2]

^ Seidman, L. S.; Skokos, C. K. (2005). „An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis”. Infectious diseases in obstetrics and gynecology. 13 (4): 197—206. PMC 1784583 . PMID 16338779. doi:10.1080/10647440500240615.
^ Butoconazole Монографија

[1] Seidman, L. S.; Skokos, C. K. (2005). „An evaluation of butoconazole nitrate 2% site release vaginal cream (Gynazole-1) compared to fluconazole 150 mg tablets (Diflucan) in the time to relief of symptoms in patients with vulvovaginal candidiasis”. Infectious diseases in obstetrics and gynecology. 13 (4): 197—206. PMC 1784583 . PMID 16338779. doi:10.1080/10647440500240615.

[2] Butoconazole Монографија

[1]

[2]

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Butokonazol

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