Ciklopiroks

Ciklopiroks

Klinički podaci
Prodajno ime	Loprox, Loprox Shampoo, Penlac, Penlac Nail Lacquer
Drugs.com	Monografija
Način primene	topikalno
Farmakokinetički podaci
Poluvreme eliminacije	1,7 h
Izlučivanje	96% renalno
Identifikatori
CAS broj	29342-05-0 Y
ATC kod	D01AE14 (WHO), G01AX12
PubChem	CID 2749
DrugBank	DB01188 Y
ChemSpider	2647 Y
ChEMBL	CHEMBL1413 Y
Hemijski podaci
Formula	C12H17NO2
Molarna masa	207,269
SMILES CC1=CC(=O)N(O)C(=C1)C1CCCCC1
InChI InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3 Y Key:SCKYRAXSEDYPSA-UHFFFAOYSA-N Y
Fizički podaci
Tačka topljenja	144 °C (291 °F)

Ciklopiroks je organsko jedinjenje, koje sadrži 12 atoma ugljenika i ima molekulsku masu od 207,269 Da.^[1][2][3][4]

1. ^ Niewerth M, Kunze D, Seibold M, Schaller M, Korting HC, Hube B: Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother. 2003 Jun;47(6):1805-17. PMID 12760852
2. ^ Sigle HC, Thewes S, Niewerth M, Korting HC, Schafer-Korting M, Hube B: Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. J Antimicrob Chemother. 2005 May;55(5):663-73. Epub 2005 Mar 24. PMID 15790671
3. ^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709 . PMID 21059682. doi:10.1093/nar/gkq1126.  уреди
4. ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958.  уреди