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Fenoldopam

Fenoldopam
IUPAC ime
(RS)-6-hloro-1-(4-hidroksifenil)-2,3,4,5-tetrahidro-1H-3-benzazepin-7,8-diol
Klinički podaci
Prodajno imeKorlopam
Drugs.comMonografija
Kategorija trudnoće
  • B
Način primeneIV
Farmakokinetički podaci
MetabolizamHepatic (CYP ne učestvuje)
Poluvreme eliminacije5 minuta
IzlučivanjeRenalno (90%) i fekalno (10%)
Identifikatori
CAS broj67227-57-0 ДаY
ATC kodC01CA19 (WHO)
PubChemCID 3341
DrugBankAPRD00969 ДаY
ChemSpider3224 ДаY
UNIIHA3R0MY016 ДаY
KEGGD07946 ДаY
ChEBICHEBI:5002 ДаY
ChEMBLCHEMBL588 ДаY
Hemijski podaci
FormulaC16H16ClNO3
Molarna masa305,76 g/mol
  • Clc1c3c(cc(O)c1O)C(c2ccc(O)cc2)CNCC3
  • InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2 ДаY
  • Key:TVURRHSHRRELCG-UHFFFAOYSA-N ДаY

Fenoldopam (Korlopam) je lek i sintetički derivat benzazepina koji deluje kao periferni selektivni parcijalni agonist/antagonist D1 receptora. On se koristi kao antihipertenziv.[1] FDA je odobrila fenoldopam 1997.[2]

  1. ^ Oliver WC, Nuttall GA, Cherry KJ, Decker PA, Bower T, Ereth MH (2006). „A comparison of fenoldopam with dopamine and sodium nitroprusside in patients undergoing cross-clamping of the abdominal aorta”. Anesth. Analg. 103 (4): 833—40. PMID 17000789. doi:10.1213/01.ane.0000237273.79553.9e. 
  2. ^ accessed November 14, 2011

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فينولدوبام Arabic Ffenoldopam Mesylad CY Fenoldopam English فنول‌دوپام FA Fenoldopam Italian ଫେନୋଲଡୋପାମ OR Fenoldopam Polish Fenoldopam Portuguese Fenoldopam SH Fenoldopam VI

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