Finasterid

Finasterid
Klinički podaci
Prodajno ime	Chibro-Proscar, Finastid, Finpecia, Propecia
Drugs.com	Monografija
Način primene	Oralno
Farmakokinetički podaci
Poluvreme eliminacije	4,5 h (3,3-13,4 h)
Izlučivanje	Renalno
Identifikatori
CAS broj	98319-26-7
ATC kod	D11AX10 (WHO), G04CB01
PubChem	CID 57363
DrugBank	DB01216
ChemSpider	51714
ChEBI	CHEBI:5062
ChEMBL	CHEMBL710
Hemijski podaci
Formula	C23H36N2O2
Molarna masa	372,544
	SMILES [H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)C=C[C@]12C; ;
	InChI InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1 ; Key:DBEPLOCGEIEOCV-WSBQPABSSA-N ;
Fizički podaci
Tačka topljenja	252—254 °C (486—489 °F)

Finasterid je organsko jedinjenje, koje sadrži 23 atoma ugljenika i ima molekulsku masu od 372,544 Da.^[1]^[2]^[3]^[4]

^ Suzuki R, Satoh H, Ohtani H, Hori S, Sawada Y: Saturable binding of finasteride to steroid 5alpha-reductase as determinant of nonlinear pharmacokinetics. Drug Metab Pharmacokinet. 2010;25(2):208-13. PMID 20460827
^ Smith AB, Carson CC: Finasteride in the treatment of patients with benign prostatic hyperplasia: a review. Ther Clin Risk Manag. 2009 Jun;5(3):535-45. Epub 2009 Jul 12. PMID 19707263
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035—41. PMC 3013709 . PMID 21059682. doi:10.1093/nar/gkq1126.
^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic acids research. 36 (Database issue): D901—6. PMC 2238889 . PMID 18048412. doi:10.1093/nar/gkm958.