Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.

Responsive image

Behavioral epigenetics

Behavioral epigenetics is the field of study examining the role of epigenetics in shaping animal and human behavior.[1] It seeks to explain how nurture shapes nature,[2] where nature refers to biological heredity[3] and nurture refers to virtually everything that occurs during the life-span (e.g., social-experience, diet and nutrition, and exposure to toxins).[4] Behavioral epigenetics attempts to provide a framework for understanding how the expression of genes is influenced by experiences and the environment[5] to produce individual differences in behaviour,[6] cognition,[2] personality,[7] and mental health.[8][9]

Epigenetic gene regulation involves changes other than to the sequence of DNA and includes changes to histones (proteins around which DNA is wrapped) and DNA methylation.[10][4][11] These epigenetic changes can influence the growth of neurons in the developing brain[12] as well as modify the activity of neurons in the adult brain.[13][14] Together, these epigenetic changes in neuron structure and function are thought to have an influence on behavior.[1]

  1. ^ a b Cite error: The named reference Miller_2010 was invoked but never defined (see the help page).
  2. ^ a b Powledge T (2011). "Behavioral epigenetics: How nurture shapes nature". BioScience. 61 (8): 588–592. doi:10.1525/bio.2011.61.8.4.
  3. ^ Kail RV, Barnfield A (2011). Children and Their Development, Second Canadian Edition with MyDevelopmentLab. Toronto: Pearson Education Canada. ISBN 978-0-13-255770-2.
  4. ^ a b Moore DS (2015). The Developing Genome: An Introduction to Behavioral Epigenetics (1st ed.). Oxford University Press. ISBN 978-0-19-992234-5.
  5. ^ Champagne FA, Mashoodh R (2012). "Genes in context: Gene-environment interplay and the origins of individual differences in behaviour". Current Directions in Psychological Science. 18 (3): 127–131. doi:10.1111/j.1467-8721.2009.01622.x. S2CID 18672157.
  6. ^ Zhang TY, Meaney MJ (2010). "Epigenetics and the environmental regulation of the genome and its function". Annual Review of Psychology. 61: 439–66, C1-3. doi:10.1146/annurev.psych.60.110707.163625. PMID 19958180.
  7. ^ Bagot RC, Meaney MJ (Aug 2010). "Epigenetics and the biological basis of gene x environment interactions". Journal of the American Academy of Child and Adolescent Psychiatry. 49 (8): 752–71. doi:10.1016/j.jaac.2010.06.001. PMID 20643310.
  8. ^ Stuffrein-Roberts S, Joyce PR, Kennedy MA (Feb 2008). "Role of epigenetics in mental disorders". The Australian and New Zealand Journal of Psychiatry. 42 (2): 97–107. doi:10.1080/00048670701787495. PMID 18197504. S2CID 36721906.
  9. ^ Mill J, Tang T, Kaminsky Z, Khare T, Yazdanpanah S, Bouchard L, Jia P, Assadzadeh A, Flanagan J, Schumacher A, Wang SC, Petronis A (Mar 2008). "Epigenomic profiling reveals DNA-methylation changes associated with major psychosis". American Journal of Human Genetics. 82 (3): 696–711. doi:10.1016/j.ajhg.2008.01.008. PMC 2427301. PMID 18319075.
  10. ^ Rana AK (24 January 2018). "Crime investigation through DNA methylation analysis: methods and applications in forensics". Egyptian Journal of Forensic Sciences. 8 (1). doi:10.1186/s41935-018-0042-1.
  11. ^ Pennisi E (Aug 2001). "Behind the scenes of gene expression". Science. 293 (5532): 1064–7. doi:10.1126/science.293.5532.1064. PMID 11498570. S2CID 40236421.
  12. ^ Juliandi B, Abematsu M, Nakashima K (Aug 2010). "Epigenetic regulation in neural stem cell differentiation". Development, Growth & Differentiation. 52 (6): 493–504. doi:10.1111/j.1440-169X.2010.01175.x. PMID 20608952. S2CID 28991168.
  13. ^ Ma DK, Marchetto MC, Guo JU, Ming GL, Gage FH, Song H (Nov 2010). "Epigenetic choreographers of neurogenesis in the adult mammalian brain". Nature Neuroscience. 13 (11): 1338–44. doi:10.1038/nn.2672. PMC 3324277. PMID 20975758.
  14. ^ Sun J, Sun J, Ming GL, Song H (Mar 2011). "Epigenetic regulation of neurogenesis in the adult mammalian brain". The European Journal of Neuroscience. 33 (6): 1087–93. doi:10.1111/j.1460-9568.2011.07607.x. PMC 3076719. PMID 21395852.

Previous Page Next Page






علم التخلق السلوكي Arabic Epigenética conductual Spanish وراژن‌شناسی رفتاری FA אפיגנטיקה התנהגותית HE د چلند ایپي‌جینیټيک PS Epigenética do comportamento Portuguese

Responsive image

Responsive image