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Names | |
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Preferred IUPAC name
O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate | |
Other names
Diethoxy-[(2-isopropyl-6-methyl-4-pyrimidinyl)oxy]-thioxophosphorane
Basudin Diazide Spectracide | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.005.795 |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C12H21N2O3PS | |
Molar mass | 304.34 g·mol−1 |
Appearance | Colorless to dark brown liquid |
Odor | faint, ester-like |
Density | 1.116-1.118 g/cm3 at 20 °C[1] |
Boiling point | decomposes[2] |
40 mg/L[3] | |
log P | 3.81 (octanol/water)[4] |
Pharmacology | |
QP53AF03 (WHO) | |
Hazards | |
Flash point | 82 °C; 180 °F; 355 K[2] |
NIOSH (US health exposure limits): | |
PEL (Permissible)
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none[2] |
REL (Recommended)
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TWA 0.1 mg/m3 [skin][2] |
IDLH (Immediate danger)
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N.D.[2] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Diazinon (IUPAC name: O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate, INN - Dimpylate), a colorless to dark brown liquid, is a thiophosphoric acid ester developed in 1952 by Ciba-Geigy, a Swiss chemical company (later Novartis and then Syngenta). It is a nonsystemic organophosphate insecticide formerly used to control cockroaches, silverfish, ants, and fleas in residential, non-food buildings. Diazinon was heavily used during the 1970s and early 1980s for general-purpose gardening use and indoor pest control. A bait form was used to control scavenger wasps in the western U.S. Diazinon is used in flea collars for domestic pets in Australia and New Zealand. Diazinon is a major component in the "Golden Fleece" brand sheep dip. Residential uses of diazinon were outlawed in the U.S. in 2004 because of human health risks[5] but it is still approved for agricultural uses. An emergency antidote is atropine.[6]
Specific Health Risks: Routes of contact for Diazinon include breathing it, consuming it, or contact with skin. The negative health effects when in contact with Diazinon includes eye watering, drool or runny nose, not having any appetite, throwing up, intense coughing, abdominal pain, or even stiffness in various muscles/paralysis.[7] Headaches can also be health risks.[8] Some other physiological effects include pinpoint pupils, increased heart rate, seizures, or even coma. Larger exposure to diazinon is known to yield these risks. If it is a smaller exposure, the symptoms may be reduced such as just a runny nose or some eye watering.[9] One thing to note is that while Diazinon has many different health risks, the EPA has not categorized it as a carcinogen.[10]