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Five-prime cap
In molecular biology, the five-prime cap (5′ cap) is a specially altered nucleotide on the 5′ end of some primary transcripts such as precursor messenger RNA. This process, known as mRNA capping, is highly regulated and vital in the creation of stable and mature messenger RNA able to undergo translation during protein synthesis. Mitochondrial mRNA[1] and chloroplastic mRNA[2] are not capped.
- ^ Temperley RJ, Wydro M, Lightowlers RN, Chrzanowska-Lightowlers ZM (June 2010). "Human mitochondrial mRNAs—like members of all families, similar but different". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797 (6–7): 1081–1085. doi:10.1016/j.bbabio.2010.02.036. PMC 3003153. PMID 20211597.
- ^ Monde RA, Schuster G, Stern DB (7 June 2000). "Processing and degradation of chloroplast mRNA". Biochimie. 82 (6–7): 573–582. doi:10.1016/S0300-9084(00)00606-4. PMID 10946108.
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