PAX7

PAX7
Identifiers
Aliases	PAX7, HUP1, PAX7B, RMS2, Pax7, paired box 7, MYOSCO
External IDs	OMIM: 167410; MGI: 97491; HomoloGene: 55665; GeneCards: PAX7; OMA:PAX7 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	18,748,866 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	139,560,839 bp
RNA expression pattern
	Top expressed in
	olfactory zone of nasal mucosa; ; nasal epithelium; ; muscle of thigh; ; testicle; ; gastrocnemius muscle; ; prefrontal cortex; ; skeletal muscle tissue; ; Brodmann area 9; ; right frontal lobe; ; cingulate gyrus;
	Top expressed in
	superior colliculus; ; somite; ; dorsal tegmental nucleus; ; urethra; ; pretectal area; ; main bronchus; ; Pituitary Gland; ; hair; ; nasal placode; ; lateral nasal prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity; RNA polymerase II general transcription initiation factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	positive regulation of myoblast proliferation; regulation of cell fate commitment; chromatin remodeling; regulation of transcription, DNA-templated; spinal cord association neuron differentiation; positive regulation of histone methylation; anatomical structure morphogenesis; muscle organ development; negative regulation of apoptotic process; transcription, DNA-templated; embryonic skeletal system development; multicellular organism development; cartilage development; skeletal muscle tissue regeneration; muscle tissue morphogenesis; regulation of gene expression; neuron fate commitment; skeletal muscle satellite cell commitment; dorsal/ventral neural tube patterning; regulation of protein binding; skeletal muscle tissue development; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of DNA binding;
	Sources:Amigo / QuickGO
Orthologs
	5081
	18509
	ENSG00000009709
	ENSMUSG00000028736
	P23759
	P47239
	NM_013945; NM_001135254; NM_002584
	NM_011039
	NP_001128726; NP_002575; NP_039236
	NP_035169
	Wikidata
View/Edit Human	View/Edit Mouse

Paired box protein Pax-7 is a protein that in humans is encoded by the PAX7 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000009709 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028736 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Stapleton P, Weith A, Urbánek P, Kozmik Z, Busslinger M (April 1993). "Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9". Nature Genetics. 3 (4): 292–8. doi:10.1038/ng0493-292. PMID 7981748. S2CID 21338655.
^ Pilz AJ, Povey S, Gruss P, Abbott CM (March 1993). "Mapping of the human homologs of the murine paired-box-containing genes". Mammalian Genome. 4 (2): 78–82. doi:10.1007/BF00290430. PMID 8431641. S2CID 30845070.
^ "Entrez Gene: PAX7 paired box gene 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000009709 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028736 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7981748-5] Stapleton P, Weith A, Urbánek P, Kozmik Z, Busslinger M (April 1993). "Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9". Nature Genetics. 3 (4): 292–8. doi:10.1038/ng0493-292. PMID 7981748. S2CID 21338655.

[pmid8431641-6] Pilz AJ, Povey S, Gruss P, Abbott CM (March 1993). "Mapping of the human homologs of the murine paired-box-containing genes". Mammalian Genome. 4 (2): 78–82. doi:10.1007/BF00290430. PMID 8431641. S2CID 30845070.

[entrez-7] "Entrez Gene: PAX7 paired box gene 7".

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PAX7

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