Our website is made possible by displaying online advertisements to our visitors.
Please consider supporting us by disabling your ad blocker.

Responsive image

Prostacyclin

Prostacyclin
Clinical data
Trade namesFlolan, Veletri
AHFS/Drugs.comMonograph
License data
Pregnancy
category
  • AU: B1
ATC code
Legal status
Legal status
Pharmacokinetic data
Elimination half-life42 seconds
Identifiers
  • (Z)-5-[(4R,5R)-5-Hydroxy-4-((S,E)-3-hydroxyoct-1-enyl)hexahydro-2H-cyclopenta[b]furan-2-ylidene]pentanoic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H32O5
Molar mass352.471 g·mol−1
3D model (JSmol)
  • OC(=O)CCC\C=C1\C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]2O1
  • InChI=1S/C20H32O5/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22/h8,10-11,14,16-19,21-22H,2-7,9,12-13H2,1H3,(H,23,24)/b11-10+,15-8-/t14-,16+,17+,18+,19-/m0/s1 ☒N
  • Key:KAQKFAOMNZTLHT-OZUDYXHBSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator.

When used as a drug, it is also known as epoprostenol.[1] The terms are sometimes used interchangeably.[2]

  1. ^ "epoprostenol" at Dorland's Medical Dictionary
  2. ^ Kermode J, Butt W, Shann F (August 1991). "Comparison between prostaglandin E1 and epoprostenol (prostacyclin) in infants after heart surgery". British Heart Journal. 66 (2): 175–178. doi:10.1136/hrt.66.2.175. PMC 1024613. PMID 1883670.

Previous Page Next Page






إيبوبروستينول Arabic پروستاسیکلین AZB Простациклин Bulgarian Prostaglandina I Catalan Prostacyclin German Prostaciclina Spanish Prostaziklina EU پروستاسیکلین FA Prostasykliini Finnish Prostacycline French

Responsive image

Responsive image