A-230

A-230
Names
	IUPAC name methyl-(1-(diethylamino)ethylidene)phosphonamidofluoridate
Identifiers
CAS Number	2387496-12-8 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:140423;
ChemSpider	64808785 ;
PubChem CID	132472359;
CompTox Dashboard (EPA)	DTXSID90896939;
	InChI InChI=1/C7H16FN2OP/c1-5-10(6-2)7(3)9-12(4,8)11/h5-6H2,1-4H3 Key: OUJDIWHRYQBZSR-UHFFFAOYNA-N;
	SMILES CCN(CC)C(C)=N[P](C)(F)=O;
Properties
Chemical formula	C7H16FN2OP
Molar mass	194.190 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

A-230 is an organophosphate nerve agent. It was developed in the Soviet Union under the FOLIANT program and is one of the group of compounds referred to as Novichok agents that were revealed by Vil Mirzayanov. A-230 is possibly the most potent nerve agent for which specific toxicity figures have been published, with a human lethal dose estimated to be less than 0.1 mg. However it was felt to be less suitable for weaponisation than other agents such as A-232 and A-234, due to issues with the liquid agent exhibiting low volatility and solidifying at low temperatures, as well as poor stability in the presence of water.^[2]^[3]^[4]^[5]^[6]

^ Chai PR, Hayes BD, Erickson TB, Boyer EW (2018). "Novichok agents: a historical, current, and toxicological perspective". Toxicology Communications. 2 (1): 45–48. doi:10.1080/24734306.2018.1475151. PMC 6039123. PMID 30003185. S2CID 49661943.
^ Mirzayanov VS (2008). State Secrets: An Insider's Chronicle of the Russian Chemical Weapons Program. Outskirts Press. ISBN 978-1-4327-2566-2.
^ Vásárhelyi G, Földi L (2007). "History of Russia's chemical weapons" (PDF). AARMS. 6 (1): 135–146. Archived from the original (PDF) on 2018-03-14.
^ Franca TC, Kitagawa DA, Cavalcante SF, da Silva JA, Nepovimova E, Kuca K (March 2019). "Novichoks: The Dangerous Fourth Generation of Chemical Weapons". International Journal of Molecular Sciences. 20 (5): 1222. doi:10.3390/ijms20051222. PMC 6429166. PMID 30862059.
^ "Земан: в Чехии производился и складировался нервно-паралитический газ "Новичок"" [Heman: The "Novichoch" nerve gas is produced and scaled up in Czechoslovakia.]. TASS, information agency (in Russian). 3 May 2018.
^ Harvey SP, McMahon LR, Berg FJ (January 2020). "Hydrolysis and enzymatic degradation of Novichok nerve agents". Heliyon. 6 (1): e03153. Bibcode:2020Heliy...603153H. doi:10.1016/j.heliyon.2019.e03153. PMC 7002793. PMID 32042950.

[chai18-1] Chai PR, Hayes BD, Erickson TB, Boyer EW (2018). "Novichok agents: a historical, current, and toxicological perspective". Toxicology Communications. 2 (1): 45–48. doi:10.1080/24734306.2018.1475151. PMC 6039123. PMID 30003185. S2CID 49661943.

[2] Mirzayanov VS (2008). State Secrets: An Insider's Chronicle of the Russian Chemical Weapons Program. Outskirts Press. ISBN 978-1-4327-2566-2.

[3] Vásárhelyi G, Földi L (2007). "History of Russia's chemical weapons" (PDF). AARMS. 6 (1): 135–146. Archived from the original (PDF) on 2018-03-14.

[4] Franca TC, Kitagawa DA, Cavalcante SF, da Silva JA, Nepovimova E, Kuca K (March 2019). "Novichoks: The Dangerous Fourth Generation of Chemical Weapons". International Journal of Molecular Sciences. 20 (5): 1222. doi:10.3390/ijms20051222. PMC 6429166. PMID 30862059.

[5] "Земан: в Чехии производился и складировался нервно-паралитический газ "Новичок"" [Heman: The "Novichoch" nerve gas is produced and scaled up in Czechoslovakia.]. TASS, information agency (in Russian). 3 May 2018.

[pmid32042950-6] Harvey SP, McMahon LR, Berg FJ (January 2020). "Hydrolysis and enzymatic degradation of Novichok nerve agents". Heliyon. 6 (1): e03153. Bibcode:2020Heliy...603153H. doi:10.1016/j.heliyon.2019.e03153. PMC 7002793. PMID 32042950.

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