Back علاج بالدم الذاتي Arabic Eigenbluttherapie German Autohemoterapia Spanish स्वरक्त चिकित्सा HI Аутогемотерапия KY Autohemotherapie Dutch Auto-hemoterapia Portuguese Аутогемотерапия Russian Автогемотерапія Ukrainian Autogemoterapiya UZ
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Autologous blood therapy, also known as autologous blood injection or autohemotherapy, comprises certain types of hemotherapy using a person's own blood (auto- + hemo- + therapy). There are several kinds, the original belonging only to traditional medicine, alternative medicine, and some newer kind of medicine under investigation. The original, unscientific form is "the immediate intramuscular or subcutaneous reinjection of freshly drawn autologous blood". It was used in the early 20th century, when some physicians believed that it had efficacy and a logical mechanism of action; it was abandoned as advancing science made clear that it lacked those. [1]
The other forms involve some change to the blood before it is reinjected, typically oxygenation, ozonation (ozonated autohemotherapy),[2][3] ultraviolet light exposure, or centrifugation. Forms include platelet-rich plasma (PRP), and autologous conditioned serum (ACS).[4]
It is possible that ozonated or UV autohemotherapy may have real efficacy and effectiveness in autoimmune diseases, if they are immunomodulatory in some way (such as by interfering with the deranged autoantibodies),[2] but this mechanism of action, if it exists, is not yet well understood;[2] it is also logical that whatever molecular changes the ozone and UV bring about are unlikely to act specifically on just the desired target molecules, meaning that risks are involved.
Although autologous blood donation and plasmapheresis are conceptually analogous, they are differentiated from autologous blood therapy in the autohemotherapy sense of that term, having thoroughly scientific bases.
- ^ A Systematic Review of Autohemotherapy as a Treatment for Urticaria and Eczema / Devon D. Brewer, Cureus 6(12): e233. doi:10.7759/cureus.233
- ^ a b c Sheikhi, A; Azarbeig, M; Karimi, H (2014), "Autohemotherapy in chronic urticaria: what could be the autoreactive factors and curative mechanisms?", Ann Dermatol, 26 (4): 526–527, doi:10.5021/ad.2014.26.4.526, PMC 4135115, PMID 25143689.
- ^ Molinari, F; et al. (2014), "Ozone autohemotherapy induces long-term cerebral metabolic changes in multiple sclerosis patients", Int J Immunopathol Pharmacol, 27 (3): 379–389, doi:10.1177/039463201402700308, PMID 25280029, S2CID 23209243.
- ^ Wehling, P; Evans, C; Wehling, J; Maixner, W (August 2017). "Effectiveness of intra-articular therapies in osteoarthritis: a literature review". Therapeutic Advances in Musculoskeletal Disease. 9 (8): 183–196. doi:10.1177/1759720X17712695. PMC 5557186. PMID 28835778.