Charles Brenton Huggins

Charles Brenton Huggins
Huggins in 1966
Born	(1901-09-22)September 22, 1901 Halifax, Nova Scotia, Canada
Died	January 12, 1997(1997-01-12) (aged 95) Chicago, Illinois, U.S.
Citizenship	Canadian, American
Alma mater	Acadia University Harvard University
Known for	prostate cancer hormones
Awards	Nobel Prize for Physiology or Medicine (1966) Cameron Prize for Therapeutics of the University of Edinburgh (1956) Gairdner Foundation International Award (1966)
Scientific career
Fields	physiology
Institutions	University of Michigan, University of Chicago

Charles Brenton Huggins (September 22, 1901 – January 12, 1997) was a Canadian-American surgeon and physiologist known for his work on prostate function, prostate cancer, and breast cancer. Born in Halifax in 1901, Huggins moved to the United States for medical school. He was one of the founding staff members of the University of Chicago Medical School, where he remained for the duration of his professional research career. Huggins' work on how sex hormones influence prostate function ultimately led to his discovery of hormone therapies to treat prostate cancer. For this finding, he was awarded the 1966 Nobel Prize for Physiology or Medicine. In addition to his work on prostate cancer, Huggins explored the relationship between hormones and breast cancer, developed an animal model for breast cancer, and developed "chromogenic substrate"s that are widely used for biochemical analyses. Huggins continued to perform research into his 90s; he died in Chicago in 1997.