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Condensin

Figure 1. An interphase nucleus (left) and a set of mitotic chromosomes (right) from human tissue culture cells. Bar, 10 μm.

Condensins are large protein complexes that play a central role in chromosome assembly and segregation during mitosis and meiosis (Figure 1).[1][2] Their subunits were originally identified as major components of mitotic chromosomes assembled in Xenopus egg extracts.[3]

  1. ^ Hirano T (2016). "Condensin-based chromosome organization from bacteria to vertebrates". Cell. 164 (5): 847–857. doi:10.1016/j.cell.2016.01.033. PMID 26919425.
  2. ^ Kalitsis P, Zhang T, Marshall KM, Nielsen CF, Hudson DF (2017). "Condensin, master organizer of the genome". Chromosome Res. 25 (1): 61–76. doi:10.1007/s10577-017-9553-0. PMID 28181049. S2CID 28241964.
  3. ^ Hirano T, Kobayashi R, Hirano M (1997). "Condensins, chromosome condensation complex containing XCAP-C, XCAP-E and a Xenopus homolog of the Drosophila Barren protein". Cell. 89 (4): 511–21. doi:10.1016/S0092-8674(00)80233-0. PMID 9160743. S2CID 15061740.

Condensin

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