Back مرض النسيج الضام Arabic Connectivopatia Catalan Kollagenose German Conectivopatía Spanish بیماری بافت همبند FA Sidekudossairaus Finnish Connectivite French Penyakit jaringan ikat ID Connettivite Italian Коллагеноз KK
| Connective tissue disease | |
|---|---|
| Other names | Connective tissue disorder, collagen vascular diseases |
 | |
| Different types of connective tissue | |
| Specialty | Rheumatology  |
Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue.[1] The body's structures are held together by connective tissues, consisting of two distinct proteins: elastin and collagen. Tendons, ligaments, skin, cartilage, bone, and blood vessels are all made of collagen. Skin and ligaments contain elastin. The proteins and the body's surrounding tissues may suffer damage when these connective tissues become inflamed.[2]
The two main categories of connective tissue diseases are (1) a set of relatively rare genetic disorders affecting the primary structure of connective tissue, and (2) a variety of acquired diseases where the connective tissues are the site of multiple, more or less distinct immunological and inflammatory reactions.
Diseases in which inflammation or weakness of collagen tends to occur are also referred to as collagen diseases. Collagen vascular diseases can be (but are not necessarily) associated with collagen and blood vessel abnormalities that are autoimmune in nature.
Some connective tissue diseases have strong or weak genetic inheritance risks. Others may be due to environmental factors, or a combination of genetic and environmental influences.
- ^ Cite error: The named reference
Britannicawas invoked but never defined (see the help page). - ^ "Connective Tissue Disorders". Cedars-Sinai. 2020-06-08. Retrieved 2024-07-16.