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Cosimo Rosselli | |
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 Cosimo Rosselli, Portrait of a Man c. 1481–82, | |
| Born | Cosimo Rosselli 1439 Republic of Florence (present-day Tuscany, Italy) |
| Died | c. 1507 (aged 68) Republic of Florence (present-day Tuscany, Italy) |
| Known for | Painting |
| Movement | High Renaissance |
Cosimo Rosselli (Italian: [ˈkɔːzimo rosˈsɛlli]; 1439–1507) was an Italian painter of the Quattrocento, active mainly in his birthplace of Florence, but also in Pisa earlier in his career and in 1481–82 in the Sistine Chapel in Rome, where he painted some of the large frescoes on the side walls.
Though generally regarded as a lesser talent in comparison to Sandro Botticelli, Pietro Perugino, and Domenico Ghirlandaio, who were all also active at the Sistine Chapel, Rosselli was still able to win large and important commission throughout his career, a testament to his high level of activity in his native Florence. Important local commissions include a fresco in the cloister of Santissima Annunziata, Florence and those in the Chapel of the Holy Blood in Sant'Ambrogio, Florence.