Glanzmann's thrombasthenia | |
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Other names | Thrombasthenia of Glanzmann and Naegeli[1] |
This condition is inherited in a autosomal recessive manner | |
Specialty | Hematology |
Glanzmann's thrombasthenia is an abnormality of the platelets.[2] It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.