Back Carcinoma pulmonar de células grandes Spanish Carcinome pulmonaire à grandes cellules French Թոքերի խոշոր բջջային քաղցկեղ HY Carcinoma polmonare a grandi cellule Italian Carcinoma de pulmão de grandes células Portuguese Карцином великих ћелија плућа Serbian
| Large-cell carcinoma | |
|---|---|
| Specialty | Oncology/pulmonology |
Large-cell lung carcinoma (LCLC), or large-cell carcinoma (LCC) in short, is a heterogeneous group of undifferentiated malignant neoplasms that lack the cytologic and architectural features of small cell carcinoma and glandular or squamous differentiation.[1] LCC is categorized as a type of NSCLC (non-small-cell lung carcinoma) that originates from epithelial cells of the lung. LCLC is histologically characterized by the presence of large, undifferentiated cells that lack distinctive features of either squamous cell carcinoma or adenocarcinoma (other types of cancers). Typically seen in LCLC tumor cells are abundant pale staining cytoplasm and prominent nucleoli. [2]
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