OPN1SW

OPN1SW
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1KPN
Identifiers
Aliases	OPN1SW, BCP, BOP, CBT, opsin 1 (cone pigments), short-wave-sensitive, opsin 1, short wave sensitive
External IDs	OMIM: 613522; MGI: 99438; HomoloGene: 1291; GeneCards: OPN1SW; OMA:OPN1SW - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	128,775,794 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	29,388,467 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Brodmann area 46; ; stromal cell of endometrium; ; retinal pigment epithelium; ; Achilles tendon; ; Descending thoracic aorta; ; apex of heart; ; prefrontal cortex; ; ganglionic eminence; ; exocrine gland;
	Top expressed in
	blastocyst; ; neural layer of retina; ; epithelium of lens; ; outer nuclear layer; ; retinal pigment epithelium; ; lumbar subsegment of spinal cord; ; embryo; ; morula; ; lumbar spinal ganglion; ; genital tubercle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; photoreceptor activity; signal transducer activity; G protein-coupled photoreceptor activity; signaling receptor activity;
Cellular component	integral component of membrane; integral component of plasma membrane; membrane; photoreceptor outer segment; photoreceptor disc membrane;
Biological process	response to stimulus; signal transduction; visual perception; retinoid metabolic process; phototransduction; detection of visible light; G protein-coupled receptor signaling pathway; cellular response to light stimulus;
	Sources:Amigo / QuickGO
Orthologs
	611
	12057
	ENSG00000128617
	ENSMUSG00000058831
	P03999
	P51491
	NM_001708; NM_001385125
	NM_007538
	NP_001699
	NP_031564
	Wikidata
View/Edit Human	View/Edit Mouse

Blue-sensitive opsin is a protein that in humans is encoded by the OPN1SW gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000128617 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000058831 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nathans J, Thomas D, Hogness DS (Apr 1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science. 232 (4747): 193–202. Bibcode:1986Sci...232..193N. CiteSeerX 10.1.1.461.5915. doi:10.1126/science.2937147. PMID 2937147.
^ Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). "Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32". Hum Genet. 93 (1): 79–80. doi:10.1007/bf00218919. PMID 8270261. S2CID 43548690.
^ "Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000128617 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000058831 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2937147-5] Nathans J, Thomas D, Hogness DS (Apr 1986). "Molecular genetics of human color vision: the genes encoding blue, green, and red pigments". Science. 232 (4747): 193–202. Bibcode:1986Sci...232..193N. CiteSeerX 10.1.1.461.5915. doi:10.1126/science.2937147. PMID 2937147.

[pmid8270261-6] Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM (Feb 1994). "Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32". Hum Genet. 93 (1): 79–80. doi:10.1007/bf00218919. PMID 8270261. S2CID 43548690.

[entrez-7] "Entrez Gene: OPN1SW opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)".

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