Percutaneous hepatic perfusion

Percutaneous hepatic perfusion (PHP) is a regionalized, minimally-invasive approach to cancer treatment^[1] currently undergoing Phase II and Phase III clinical testing. PHP treats a variety of hepatic tumors by isolating the liver and exposing the organ to high-dose chemotherapy. As demonstrated in clinical trials, patients treated by PHP can tolerate much higher doses of chemotherapeutic agents than those receiving traditional systemic chemotherapy without increased toxicities.^{[citation needed]}